Boston Strategics Corporation Initiates a Phase 1 Clinical Trial of the Anti-cancer Agent “FF-10501” for FUJIFILM in Patients with Advanced Hematologic Malignancies

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BOSTON–(BUSINESS WIRE)–Boston Strategics Corporation (BSC), a primary global strategic drug development provider for FUJIFILM Pharmaceuticals U.S.A., Inc. (FPHU), has begun a Phase 1 clinical trial of FUJIFILM’s anti-cancer agent FF-10501 in the United States in patients with advanced hematologic malignancies, such as relapsed or refractory high-risk myelodysplastic syndromes (MDS). The trial is carried out at the University of Texas MD Anderson Cancer Center (MD Anderson) with Guillermo Garcia-Manero, M.D., Professor, as the Principal Investigator. Prof. Garcia-Manero is a world-renowned expert in advanced hematologic malignancies, especially MDS.

MDS is a type of hematologic malignancy, in which the disorder of blood-forming “hematopoietic stem cells” causes inefficient production of blood cells triggering cytopenia.  It is also a refractory disease for some patients with poor prognosis, progressing to acute myeloid leukemia. The U.S. incidence of MDS is 60,000 cases per year, most of them in the senior age group.  FF-10501 is expected to inhibit the growth of hematological cancer cells and promote their differentiation to normally functioning cells.

MD Anderson is one of the world’s top general cancer centers with over 10,000 patients enrolled in therapeutic clinical trials each year and approximately 20,000 employees. BSC is able to utilize the world’s top-level clinical testing functions available at the MD Anderson under a Strategic Alliance Agreement to carry out Phase 1 and early Phase 2 clinical trials to gain preliminary safety information and clinical activity in cancer patients. “We are very excited to be collaborating with FPHU and BSC on this important clinical trial in patients with advanced hematologic malignancies,” said Prof. Guillermo Garcia-Manero. “This drug will provide another alternative for patients who have failed conventional chemotherapeutic approaches, and we are pleased to be furthering this research at our institution.” 

This clinical trial is the first example of a BSC and FPHU collaboration, whereby BSC optimizes and executes the global strategy of FPHU Oncology drug development programs. Utilizing Boston Strategics’ internal oncology development expertise and its ability to leverage the “True” Open Innovation™ network to collaborate with the best resources around the world, BSC will be able to deliver to FPHU more efficient and superior outcomes to cancer patients worldwide.

“This is a important milestone in BSC and FPHU partnership to develop a new pharmaceutical R&D platform for FPHU, which looks for an innovative and efficient way for global development of FUJIFILM’s unique oncology pipeline“, says Eita Kitayama, President of Boston Strategics. “Both companies are fully committed to deliver breakthrough therapies using innovative approaches to achieve industry benchmark-beating timelines, quality, and financial investments for important novel anti-cancer agents.”

Contact:
Strategia Therapeutics, Inc.
+1-781-761-0123 (office)
Contact@StrategiaTx.com (email)
http://www.StrategiaTx.com (website)

Boston Strategics Corporation Announces Licensing Deal with Eisai Co., Ltd.

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BOSTON–(BUSINESS WIRE)–Boston Strategics Corporation (BSC), an integrated clinical-stage drug research and development (R&D) company, Boston, MA, today announced that it has entered into an exclusive licensing and development agreement with Japanese global pharmaceutical company Eisai Co., Ltd., for Eisai’s oncology drug, E6201.

E6201 is a dual-targeted FLT3 and MEK inhibitor which has completed a Phase1 clinical trial showing preliminary antitumor activity and an acceptable safety profile. Building on a strong scientific rationale supported by recent preclinical data, BSC will undertake a clinical Proof of Concept (PoC) trial in the high unmet need FLT3 mutated AML patients.

Under this agreement with Eisai, BSC has worldwide rights to develop and commercialize E6201 for all Oncology indications.

This collaboration is a prime example of BSC applying its “True” Open Innovation™ platform to develop drug candidates with potential to significantly improve patients’ health care. As such it represents the next step toward BSC’s vision to create a novel and comprehensive approach to global pharmaceutical development.

“This is a critical milestone for BSC to validate our concept to move drug development programs forward by increasing the Probability of Success (PoS) and sharing risks with key strategic partners,” says Eita Kitayama, President of Boston Strategics. “Eisai recognized the value of this approach and entrusted BSC with the development of E6201 for cancer indications to build on the foundation of this new platform. At BSC, we are deeply committed to proving that our innovative approaches can deliver breakthrough therapies with industry benchmark-beating timelines, quality, and financial investments, thus limiting the ever increasing costs of pharmaceutical innovation and development.”

Contact:
Strategia Therapeutics, Inc.
+1-781-761-0123 (office)
Contact@StrategiaTx.com (email)
http://www.StrategiaTx.com (website)

Boston Strategics Announces Oncology Drug Development Partnership with FUJIFILM Pharmaceuticals U.S.A.

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BOSTON–(BUSINESS WIRE)–Boston Strategics Corporation, an integrated research and development biotechnology company, Boston, MA, today announced a new drug development partnership with FUJIFILM Pharmaceuticals U.S.A., Inc. (FPHU), Boston, MA, a global pharmaceutical development center of FUJIFILM Corporation, Tokyo, Japan. This strategic collaboration is the first of its kind between a Japanese pharmaceutical company and a pharmaceutical research and development provider, creating a novel and comprehensive approach to global pharmaceutical development.

Under this agreement, Boston Strategics will be the primary provider for FPHU global drug development services and resources for FPHU Oncology programs. This agreement will build on Boston Strategics strengths covering the spectrum from preclinical and early clinical development through Phase I and II human Proof-of-Concept (POC). Utilizing Boston Strategics’ internal oncology development expertise and ability to identify and collaborate with the best resources around the world, FPHU will expand its global reach in oncology drug development.

Boston Strategics will optimize and execute the global strategy of FPHU Oncology drug development programs. In this capacity, Boston Strategics will leverage its “True Open Innovation™” network to deliver superior outcomes, using highly efficient execution strategies and proven partners, such as the University of Texas MD Anderson Cancer Center, Houston TX (MD Anderson).

“True Open Innovation™ overcomes any limitations by reducing the need for large infrastructure, and draws on critical drug development expertise based on the unique needs of a particular program,” says Keizo Koya, Ph.D., CEO of Boston Strategics. “Our strong business relationships with our global resource networks are poised to assist pharmaceutical/biotech companies with strategy and launch of quality global drug development programs, and rapidly execute them to the next decision step/value inflection point. We are deeply committed to giving a new pharmaceutical R&D platform for FPHU, which look for an innovative and efficient way of globally developing their unique oncology pipelines. Entering into a special alliance of Boston Strategics this year with MD Anderson, a world leader in cancer treatment and oncology research, Boston Strategics will use this opportunity to provide global clinical development supports for FPHU.”

The ultimate goal of this unique partnership is to develop FUJIFILM’s oncology drug candidates globally using innovative approaches coupled with industry benchmark-beating timelines, quality, and financial investment.

Contact:
Strategia Therapeutics, Inc.
+1-781-761-0123 (office)
Contact@StrategiaTx.com (email)
http://www.StrategiaTx.com (website)

Boston Strategics Announces Strategic Alliance with UT MD Anderson for Oncology Drug Development

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BOSTON–(BUSINESS WIRE)–Boston Strategics Corporation announced today a strategic alliance with the University of Texas MD Anderson Cancer Center to facilitate oncology drug development by integrating the translational and clinical oncology development expertise and resources of MD Anderson with the “True Open Innovation” network built by Boston Strategics.

Under this agreement, Boston Strategics will optimize and execute the global drug development of its pharmaceutical and biotechnology clients by leveraging its “True Open Innovation” network todeliver superior outcomes using its highly efficient execution strategies in partnership with MD Anderson.

Building truly collaborative translational and clinical development programs is one of the main tenets of Boston Strategics’ efficient approach to drug development that values the importance of the clinical investigators’ input to optimize drug development.

MD Anderson’s leadership in translational research and in precision medicine with the newly created Institute for Personalized Cancer Therapy will permit tailoring of Boston Strategics’ cancer therapies to appropriate patient populations.

This agreement underscores Boston Strategics commitment to partnering with academic and medical institutions to build a global network of experts and institutions dedicated to improving the treatment of cancer and management of patients.

“By combining the strengths of the MD Anderson Cancer Center with the oncology drug development expertise and true open innovation network of Boston Strategics, we are creating a new, efficient, streamlined model for global oncology clinical development,” says Eita Kitayama, President ofBoston Strategics. “This is an innovative and unique collaboration that will translate the highest-quality science into proven clinical success in an efficient and agile manner, while enhancing the competitive position of our Pharma and Biotech clients in the ever increasing challenging environment of clinical drug development.”

The ultimate goal of this partnership is to deliver new therapeutic approaches to oncology patients globally with industry benchmark-beating timelines and financial investment giving Boston Strategics’ local and global partners a fast and efficient path to developing their compounds globally.

“MD Anderson is keen on collaborating with partners willing to establish long-term commitments to the institution,” said Ferran Prat, MD Anderson vice president for strategic industry ventures. “We believe in the power of industry and academia coming together, and coming up with solutions to enhance efficiencies and achieve faster development times. This partnership allows the organizations to work closely in a collaborative fashion to reach those goals.”

About Boston Strategics

Boston Strategics is an integrated biotechnology research and development company with experience in developing, managing and optimizing global drug development programs from late discovery, through translational research, first-in-man proof-of-concept studies. Boston Strategicshas established collaborations with several major Japanese pharmaceutical partners.

About MD Anderson

MD Anderson provides care for approximately 100,000 patients each year. In FY 2012, nearly 8,500 of its patients participated in clinical trials exploring novel treatments, the largest such program in the nation.

Contact:
Strategia Therapeutics, Inc.
+1-781-761-0123 (office)
Contact@StrategiaTx.com (email)
http://www.StrategiaTx.com (website)