Strategia Therapeutics makes major paradigm shift in new drug R&D

Strategia Therapeutics makes major paradigm shift in new drug R&D

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The pharmaceutical industry faces a tough challenge as the current drug development process is highly inefficient and very cost prohibitive. The average cost from R&D until market approval is $4 billion and the success rate for approval by the U.S. Food and Drug Administration stands at only 5 percent.

Keizo's propile photoThe increase in R&D cost has come at an 80-fold decrease in productivity over the last nine years alone.

Strategia Therapeutics, a Boston-based company, has initiated an innovative approach to R&D and is changing the traditional model of drug development.

“Collaboration is the key to success. Remember the days when movies were primarily created by big studios? Actors, musicians, writers and directors worked under one company because people believed they needed to be vertically integrated and have large infrastructures to make good films. Now, movies are made by individuals with varied backgrounds who collaborate with one another,” said President and CEO Dr. Keizo Koya.

“Similarly, Strategia believes in the power of collaboration. Strategia gathers top-notch scientists, drug developers, medical doctors and investors from all over the world to produce and manage the best development team for each new drug, without large infrastructure and expenditure,” Koya added.

With that vision, Strategia has since established seven teams for seven drug candidates in three years by collaborating with experts, organizations, and companies such as Fujifilm,Eisai and MD Anderson Cancer Center.

“We reject the one-size-fits-all mentality. We handpick the experts who are best for each individual drug that we develop,” said Koya.

By translating the highest quality science into proven clinical success in an efficient and nimble manner for patients, Strategia’s innovative approach will bring significant benefits not only to the patients, but also to all the collaborators, investors and society at large.

 

Strategia Therapeutics Spins Out SOLA Biosciences to Commercialize Tapboost® Technology

Strategia Therapeutics Spins Out SOLA Biosciences to Commercialize Tapboost® Technology

BOSTON–(BUSINESS WIRE) – Strategia Therapeutics Inc. (Strategia) announced its first spinout company, SOLA Biosciences LLC (SOLA). Headquartered in Boston, SOLA focuses on Tapboost® technology and globally collaborates with various pharmaceutical companies and researchers.

Strategia is an innovative pharmaceutical R&D company that provides strategy, management, and optimization of global drug development programs with a new model for collaborative drug development by bringing together small, specific global expert teams for each drug project. Strategia has developed its proprietary technology, Tapboost®, to control protein folding and the protein production process. This breakthrough platform significantly improves targeted protein production such as antibodies and Fc-fusion proteins.

“We have discovered the amino acid chaperone motifs that enhance protein production only for targeted proteins or antibodies of interest,“ says Dr. Akinori Hishiya, Principal Scientist of SOLA. “Our data shows enhanced expression more than 10-20 times for various “difficult-to-express” proteins such as FVIII-Fc.”

SOLA has established ten MTAs (material transfer agreements) so far with pharmaceutical and biotech companies including major ones to evaluate the Tapboost® technology for their therapeutic biologics and new target molecules.

“One of the reasons we have spun out the SOLA from Strategia is that while SOLA focuses on the application of the Tapboost® technology, Strategia will be able to focus more on its mission which is to swiftly create needed drugs for the patients at lower cost,” says Dr. Keizo Koya, President and CEO of Strategia. “The other primary reason is that Tapboost® technology could accelerate the R&D process of other companies and research, not just for Strategia. Our technology will also decrease the cost of biologics since it can express protein more productively than before. There is an expected wide application range of Tapboost® technology, which will contribute to science, researchers, R&D companies, and most importantly, people who benefit from their hard work.”

About Strategia Therapeutics, Inc. (Strategia)
Strategia is an integrated pharmaceutical company with the goal of delivering new therapeutics faster, more efficiently, and at lower overall cost to the drug development process than existing R&D big pharma models. Strategia organizes small, dedicated teams of global experts specific for each new therapeutic project to guide strategy, quality, research & development, and commercialization. This approach streamlines existing R&D and allows us to bring exciting new investigational therapeutics to patients more rapidly and efficiently.

Contact:
Strategia Therapeutics, Inc.
+1-781-761-0123 (office)
Contact@StrategiaTx.com (email)
http://www.StrategiaTx.com (website)

SOLA BioSciences, LLC.
Contact@Sola-bio.com (email)
http://sola-bio.com (Website)

Strategia starts phase I of Fujifilm cancer candidate

Strategia starts phase I of Fujifilm cancer candidate

By Michael Fitzhugh, Staff Writer

Bioworld Today pictureStrategia Therapeutics Inc., of Boston, has started a U.S.-based phase I trial of the antimetabolite agent FF-10502 in patients with advanced solid tumor cancers and lymphoma. The drug, which inhibits DNA synthesis, was first developed by Fujifilm Pharmaceuticals U.S.A. Inc. and has demonstrated preclinical activity against tumors resistant to gemcitabine therapy.
The company is working closely on the project with a researcher at the University of Texas M.D. Anderson Cancer Center, Strategia’s partner on a second project, and a researcher at the Sarah Cannon Research Institute in Denver.
Strategia, formerly called Boston Strategic Corp., is serving in the role of a contract research organization for FF-10502, testing of which will be sponsored by Fujifilm. But the company is also in-licensing programs, as it has with E6201, a dual-inhibitor of FMS-like tyrosine kinase 3 (FLT-3) and mitogen-activated protein (enzyme) kinase (MEK), first developed by Eisai Co. Ltd. for melanoma and later deprioritized by that company, opening the way for Strategia to negotiate worldwide rights to develop and commercialize it for all oncology indications.
“For me, it’s not really important which model we’re talking about,” Strategia’s founder, president and CEO, Keizo Koya, told BioWorld Today. “To me, paradigm shift is more important,” he said.
Koya, a pharma R&D veteran, established Strategia in 2012 to advance an efficient and cost-effective approach to R&D with the goal of tackling the problems of declining R&D productivity and inefficient allocations of infrastructure.

He likened the problems facing big pharma to those of the movie industry, where infrastructure and talent were long concentrated in just a handful of big studios. A much better approach, he posited, would be to source the best talents as needed, project by project.

Today, Strategia pursues a collaborative development model, bringing together small, global expert teams, each of which has expertise specific to a single drug. The goal, Koya said, is to rapidly and successfully move each project to completion while keeping internal infrastructure small and streamlined.
To make it easier to hew to his ideals, Koya hasn’t raised any outside funds for Strategia.
“Money has power,” he said. “I really want to create a new R&D platform for patients and the future of society.” That’s also why he sought to work with companies such as Fujifilm, one of his former employers, which he said has good drug candidates but, because it is a relatively new player in the pharmaceutical industry, has yet to build big infrastructure that would encumber it.
So far, Strategia has established seven teams for seven drug candidates in three years by collaborating with experts, organizations and companies such as Fujifilm, Eisai and MD Anderson. And the company is keeping plenty busy.

On Jan. 15, it initiated a phase I trial of the radioimmunotherapeutic FF-21101 for Fujifilm in patients with advanced cancers. It is also working on FF-10501, currently in phase I testing for patients with relapsed or refractory myelodysplastic syndromes and acute myeloid leukemia.
The company also has some phase II programs in the wings that it has yet to disclose and, where it finds success, may carry programs ahead to phase IIb studies.
By working with a staff of just 10 people, Koya said, Strategia can remain flexible. “If 10 people can handle 10 projects, then people of younger generations can think, ‘Keizo can do this kind of thing, so I can do much better in the future! We don’t need a big pharmaceutical company, just a small team to make a better drug.’”

Strategia Therapeutics Initiates a Phase 1 Clinical Trial of the Anti-cancer Agent “FF-10502″ For FUJIFILM in Patients with Advanced Cancers

Strategia Therapeutics Initiates a Phase 1 Clinical Trial of the Anti-cancer Agent “FF-10502″ For FUJIFILM in Patients with Advanced Cancers

BOSTON–(BUSINESS WIRE) – Strategia Therapeutics (Strategia), a primary global strategic drug development provider for FUJIFILM Pharmaceuticals U.S.A., Inc. (FPHU), has initiated a Phase 1 clinical trial of FUJIFILM’s anti-cancer agent FF-10502 in the United States in patients with advanced solid tumor cancers and lymphoma. The trial is being performed under the direction of Drs. Filip Janku, M.D. and Gerald Falchook, M.D. as Co-Principal Investigators. Dr. Janku is Assistant Professor in the Department of Investigational Therapeutics at MD Anderson Cancer Center, Houston, TX, and Dr. Falchook is Director, Drug Development Program, Sarah Cannon Research Institute, Denver, CO. Both Drs. Janku and Falchook are experts in early phase cancer clinical research studies of novel new agents.
FF-10502 is an antimetabolite anti-cancer drug that inhibits DNA synthesis. It has demonstrated preclinical activity against tumors resistant to gemcitabine therapy, a common anti-cancer agent used in the treatment of lymphoma and advanced ovarian, metastatic breast, locally advanced and metastatic lung and pancreatic cancers.
“We are very excited to be collaborating with FPHU and Strategia on this important clinical trial in patients with advanced solid tumors and lymphomas,” said Gerald Falchook, M.D. “This drug may provide another alternative for patients who have failed conventional chemotherapeutic approaches, and we are pleased to be furthering this research at our institution.”
“Strategia is pleased to initiate this important clinical trial for FPHU with these two esteemed investigators at such prestigious institutions”, said Thomas J. Myers, MD, Strategia Chief Medical Officer. “FF-10502 has shown activity against important gemcitabine-resistant cancers, and we are now poised to bring this investigational new drug to patients in the clinical setting.”

About Strategia Therapeutics, Inc. (Strategia)
Strategia is an integrated pharmaceutical company with the goal of delivering new therapeutics faster, more efficiently, and at lower overall cost to the drug development process than existing R&D big pharma models. Strategia organizes small, dedicated teams of global experts specific for each new therapeutic project to guide strategy, quality, research & development, and commercialization. This approach streamlines existing R&D and allows us to bring exciting new investigational therapeutics to patients more rapidly and efficiently.

Contact:
Strategia Therapeutics, Inc.
+1-781-761-0123 (office)
Contact@StrategiaTx.com (email)
http://www.StrategiaTx.com (website)

Strategia Therapeutics Initiates a Phase 1 Clinical Trial of the Radioimmunotherapeutic “FF-21101″ For FUJIFILM in Patients with Advanced Cancers

Strategia Therapeutics Initiates a Phase 1 Clinical Trial of the Radioimmunotherapeutic “FF-21101″ For FUJIFILM in Patients with Advanced Cancers

BOSTON–(BUSINESS WIRE) – Strategia Therapeutics (Strategia), a primary global strategic drug development provider for FUJIFILM Pharmaceuticals U.S.A., Inc. (FPHU), has initiated a Phase 1 clinical trial of FUJIFILM’s radioimmunotherapeutic agent FF-21101 in the United States in patients with advanced solid tumor cancers. The trial is being performed at The University of Texas MD Anderson Cancer Center with Vivek Subbiah, M.D., as the Principal Investigator. Dr. Subbiah is an Assistant Professor in the Department of Investigational Therapeutics and an expert in Phase 1 cancer clinical research of molecularly-targeted radiopharmaceuticals.

P-cadherin is a protein that is over-expressed in many common types of cancer, including lung, pancreatic and colon cancers, and is implicated in tumor growth and cancer disease progression. FF-21101(90Y) is a combination agent containing a monoclonal antibody against P-cadherin radiolabeled with Yttrium-90 (90Y). FF-21101(90Y) inhibits the growth of P-cadherin-expressing solid tumor cancers and, conjugated with the radionuclide, is expected to be more effective than an antibody therapy targeted to P-cadherin alone.

MD Anderson is one of the world’s top general cancer centers with over 10,000 patients enrolled in therapeutic clinical trials each year and approximately 20,000 employees. Strategia is able to utilize one of the world’s top-level clinical testing facilities at MD Anderson under a Strategic Alliance Agreement to carry out the Phase 1 clinical trial to gain safety and preliminary proof of activity in cancer patients at an early stage.

“Radioimmunotherapeutic antibody drug conjugates are a relatively new approach for clinical investigational research, with the success of drugs targeting CD20, like Zevalin®, Bexxar® and the newer investigational agents that target solid tumor cell surface markers conjugated to a radionuclide. Coupling a radionuclide with targeted drug therapy is expected to be more effective than either modality alone and an important next step for newer targeted antibody-radionuclide conjugate therapeutics for the treatment of advanced solid tumors“, said Dr. Linda Paradiso, Chief Operating Officer for Strategia.

About Strategia Therapeutics, Inc. (Strategia)
Strategia is an integrated pharmaceutical company with the goal of delivering new therapeutics faster, more efficiently, and at lower overall cost to the drug development process than existing R&D big pharma models. Strategia organizes small, dedicated teams of global experts specific for each new therapeutic project to guide strategy, quality, research & development and commercialization. This approach streamlines existing R&D and allows us to bring exciting new investigational therapeutics to patients more rapidly and efficiently.

Contact:
Strategia Therapeutics, Inc.
+1-781-761-0123 (office)
Contact@StrategiaTx.com (email)
http://www.StrategiaTx.com (website)

Strategia Therapeutics Announces Progress in a Phase 1 Clinical Trial of the Anti-cancer Agent “FF-10501-01” for FUJIFILM in Patients with Advanced Hematologic Malignancies

Strategia Therapeutics Announces Progress in a Phase 1 Clinical Trial of the Anti-cancer Agent “FF-10501-01” for FUJIFILM in Patients with Advanced Hematologic Malignancies

BOSTON–(BUSINESS WIRE) – Strategia Therapeutics, Inc. (Strategia), is announcing progress in a Phase 1 clinical trial of FUJIFILM’s anti-cancer agent, FF-10501-01 in the United States in patients with relapsed or refractory myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). The emerging results reveal that, in the Phase 1 dose escalation phase thus far (5 dose cohorts), FF-10501-01 has been highly tolerable and has demonstrated promising preliminary efficacy.

These results were published at the 57th American Society of Hematology Meeting by Professor Guillermo Garcia-Manero MD, Principal Investigator, University of Texas MD Anderson Cancer Center.

Strategia is a primary global strategic drug development provider for FUJIFILM Pharmaceuticals U.S.A., Inc. (FPHU) facilitated the preclinical study in hypo-methylating agent (HMA) resistant leukemia cell lines as well as the design and execution of the Phase 1 clinical trial of FF-10501-01 in patients with hematologic malignancies in the United States both conducted at MD Anderson Cancer Center.

In the preclinical study, FF-10501-01 produced potent anti-proliferative and pro-apoptotic effects in AML cell lines through inhibition of de novo guanine nucleotide synthesis, with similar positive effects in HMA-resistant AML cell lines.

In the Phase 1 study, a total of 5 dose cohorts have been enrolled (50 – 400 mg/m2 orally twice daily) in 17 patients (13 AML, 4 MDS). Although the trial is still underway, preliminary findings thus far are:
• FF-10501-01 has been well-tolerated to date
• FF-10501-01 produced 2 PRs lasting 2 cycles among 13 patients with relapsed/refractory AML, and 4 patients remain on treatment after 5 -15 cycles
• FF-10501-01 produced 1 bone marrow CR among 4 patients with relapsed/refractory MDS
• PK parameters for FF-10501-01 were linear across the dose range tested
• PD analysis showed potent xanthosine monophosphate suppression in patients receiving ≥ 50 mg/m2 BID

Additional Phase 1 dose cohorts of 500, 600 and 800 mg/m2 BID will be assessed. The Phase 2 portion of the study will open when a recommended Phase 2 dose is determined.

“We are deeply committed to giving our new pharmaceutical R&D platform for FPHU which looks for an innovative and efficient way of globally developing their unique oncology pipelines such as FF-10501-01.” says Dr. Keizo Koya, CEO of Strategia. “Our special alliance and innovative collaboration with MD Anderson and Fujifilm will translate the highest-quality science into proven clinical success in an efficient and nimble manner for patients in needs.”

About Strategia Therapeutics, Inc. (Strategia)
Strategia is an innovative pharmaceutical R&D company with experience in developing, managing and optimizing global drug development programs. Its mission is to create a new model for collaborative drug development by bringing together small, global expert teams, each of which has expertise specific to a single drug. By focusing its efforts in this way, Strategia rapidly and successfully moves each project forward to completion while keeping internal infrastructure small and streamlined.

Contact:
Strategia Therapeutics, Inc.
+1-781-761-0123 (office)
Contact@StrategiaTx.com (email)
http://www.StrategiaTx.com (website)

New Website Launch

Strategia Therapeutics Announces New Website Launch

BOSTON–(BUSINESS WIRE) – Strategia Therapeutics Inc. (Strategia) today announced the launch of a new, redesigned version of its website, www.strategiatx.com. The new Startegia site offers a clearer and more attractive design, easy-to-navigate functionality, and a content-rich site experience with various updated information such as its mission, patient-centric approach, global team approach, team members and capabilities of Strategia, Medical Advisory Board (MAB), featured program, and Tapboost® technology written in both English and Japanese.

“We are excited about our new website launch and the robust information it provides for clients, investors, partners, and media to better understand Strategia, says President and CEO Keizo Koya, Ph.D. “The new website and brand refresh are more closely aligned with the company’s strategic vision for growth and expansion over the next decade, and beyond. Strategia’s vision is to change the existing drug research and development paradigm. By creating a nimble approach to drug development, the pharmaceutical R&D team produced by Stratrgia can reduce overall costs and time to market, thereby making new, affordable drugs available to patients whose medical needs would otherwise be unmet.”

“It is a great pleasure to collaborate with Strategia to create a new designed Website.” says Diane Fassino, President of Fassino/Design. “The team members and their innovative approach to dramatically improving current pharmaceutical R&D for patients are amazingly inspiring. The new website hopefully helps excellent people in the world to share their values and partner with Strategia’s team to develop new effective drugs for patients in need. Strategia’s new logo is a direct representation of their team approach as well as their vision of a brighter future.”

Strategia’s approach is a dramatic break from existing R&D models. Instead of using one vertical organization to create many different drugs, Strategia pulls together customized global project teams for each new therapeutic agent under development. These teams, which Strategia manages, are made up of partners with specific expertise relevant to a certain drug or medical condition.

“We place drug development strategy first,” says Koya. “This approach streamlines existing research and development extensively, and it lets Strategia create new, effective therapeutics faster and more efficiently than ever before,” he adds. “Our primary goal is positively impacting patient health—so our success is measured by how quickly and effectively we make new drugs accessible to those patients,” he says.

The new www.strategiatx.com allows for more potential partners and clients to easily understand innovative approach of the new global pharmaceutical R&D to successfully and efficiently develop new pharmaceutical drugs for patients in need.

About Strategia Therapeutics, Inc. (Strategia)
Strategia is an innovative pharmaceutical R&D company with experience in developing, managing and optimizing global drug development programs. Its mission is to create a new model for collaborative drug development by bringing together small, global expert teams, each of which has expertise specific to a single drug. By focusing its efforts in this way, Strategia rapidly and successfully moves each project forward to completion while keeping internal infrastructure small and streamlined.

Contact:
Strategia Therapeutics, Inc.
+1-781-761-0123 (office)
Contact@StrategiaTx.com (email)
http://www.StrategiaTx.com (website)

Oncology/Hematology Medical Advisory Board

Strategia Therapeutics Forms Oncology/Hematology Medical Advisory Board

BOSTON–(BUSINESS WIRE) – Strategia Therapeutics, Inc. (Strategia) is an innovative pharmaceutical R&D company that provides strategy, management and optimization of global drug development programs with a new model for collaborative drug development by bringing together small, specific global expert teams for each drug project. Strategia announced today the formation of its first oncology/hematology Medical Advisory Board (MAB) to provide strategic medical/scientific advice and counsel to the Strategia board of directors and senior management team. The oncology/hematology MAB is comprised of three recognized oncology/hematology experts from leading academic facilities and research institutions. All three individuals have devoted their time and medical expertise to improving the lives of people afflicted with cancer and hematologic malignancies.
The three member board, chaired by Dr. Daniel D. Von Hoff, includes:

Daniel D. Von Hoff, MD, FACP, Physician in Chief, Distinguished Professor at TGen (Translational Genomics Research Institute) in Phoenix, Arizona, Chief Scientific Officer for US Oncology Research and for Honor Health’s Clinical Research Institute, Professor of Medicine, Mayo Clinic, Scottsdale, AZ. He and his colleagues were involved in the initial development of mitoxantrone, fludarabine, paclitaxel, docetaxel, gemcitabine, irinotecan, nelarabine, capecitabine, lapatinib, nab-paclitaxel, vismodegib and others. Dr. Von Hoff is an internationally recognized expert in pancreatic cancer. Dr. Von Hoff has published more than 620 papers, 137 book chapters and over 1050 abstracts. He received the 2010 David A. Karnofsky Memorial Award from the American Society of Clinical Oncology for his outstanding contributions to cancer research leading to significant improvement in patient care. Dr. Von Hoff is the past President of the American Association for Cancer Research (the world’s largest cancer research organization).

Alan F. List, MD, President and Chief Executive Officer of Moffitt Cancer Center in Tampa, FL. Dr. List is internationally recognized as an expert in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). His pioneering work led to the development of lenalidomide (Revlimid®) from the laboratory to clinical approval. Dr. List previously served as Executive Vice President and Physician-in-Chief, Vice Deputy Physician-in-Chief, and Chief of the Malignant Hematology Division at Moffitt, where he holds the Morsani Endowed Chair. He is the author of more than 300 peer-reviewed articles and the Clinician’s Manual on Myelodysplastic Syndromes (2008).

Alex A. Adjei, MD, PhD, FACP, Professor of Oncology and Chair of the Department of Medicine as well as Senior Vice-President for Clinical Research at the Roswell Park Cancer Institute (RPCI) in Buffalo, NY, the Katherine Anne Gioia Chair in Cancer Medicine at RPCI, Professor of Medicine and an Academic Scholar in Medicine at the State University of New York in Buffalo. Dr Adjei has served as chair or vice-chair in a number of US National Cancer Institute committees. He is currently the co-chair of the Thoracic Malignancies Steering Committee. He is the Editor-in-Chief of the Journal of Thoracic Oncology and a member of the Board of Directors of the International Association for the Study of Lung Cancer (IASLC). He has a long track record in experimental therapeutics and early phase oncology drug development. He received the first ASCO Drug Development Research Professorship in 2012. He has authored 227 publications dealing primarily with preclinical pharmacology, phase I trials and novel therapeutics/phase II trials of lung cancer.

“I am glad to see the Strategia team pursuing some agents which have already demonstrated anticancer activity in their initial Phase 1 trials. Those leads need to be followed”, said Dr. Daniel D. Von Hoff, MAB Chair.

“Strategia Therapeutics’ patient-focused approach to new therapy development is extraordinary and is complimented by a breadth of exciting agents in their pipeline,” Dr. Alan F. List stated.

“It is a distinct pleasure to be a member of the Strategia oncology/hematology MAB,” Dr. Alex A. Adjei stated; “Strategia’s new drug development approach and vision is truly refreshing, as it places patient benefit as the primary focus of all decision-making. I am honored to contribute to what Strategia is trying to do for patients.”

“The medical/scientific advice and guidance provided by these 3 experts will assist Strategia in properly selecting and executing the development of novel agents for patients. In addition, it will further support the mission of Strategia Therapeutics: to help patients in need by accelerating the research and development of high quality, clinically viable drugs for truly unmet needs.” says Thomas Myers, MD, FACP, Chief Medical Officer of Strategia.

Together, Strategia and the Medical Advisory Board believe that they can change the future of the pharmaceutical industry with a new model for effective drug research and development for patients and their providers.

About Strategia Therapeutics, Inc. (Strategia)

Strategia is an innovative pharmaceutical R&D company with experience in developing, managing and optimizing global drug development programs. Its mission is to create a new model for collaborative drug development by bringing together small, global expert teams, each of which has expertise specific to a single drug. By focusing its efforts in this way, Strategia rapidly and successfully moves each project forward to completion while keeping internal infrastructure small and streamlined.

Contact:
Strategia Therapeutics, Inc.
+1-781-761-0123 (office)
Contact@StrategiaTx.com (email)
http://www.StrategiaTx.com (website)

Strategia Therapeutics presents E6201 at 2015 Texas Life Science Forum

Strategia Therapeutics presents E6201, a targeted TKI for acute myeloid leukemia, at the 2015 Texas Life Science Forum

Strategic Therapeutics, inc. (ST) was founded as Boston Strategics Corporation in Massachusetts in April 2012, and in November, 2013, opened an office in Houston in the vicinity of the Texas Medical Center. The company name was changed in 2015 more accurately describe the company’s vision to change the existing drug research and development paradigm by creating a nimble approach to drug development, the reducing overall costs and time to market, and making new drug products available to patients whose medical needs would otherwise be unmet.

ST is an integrated R&D company that utilizes the expertise of its highly experienced core staff to support pharmaceutical and biotech drug development. ST can significantly optimize drug development with its streamlined structure and team of in-house drug development experts who have over 140 years’ experience in biologic and small molecule cancer drug development from discovery to global approval and life-cycle management.

The initial focus of ST has been to develop partnerships with medium size Japanese pharmaceutical companies, assisting with their strategic and tactical drug development needs in the U.S. ST has strong links to Texas, including a Strategic Alliance Agreement with MD Anderson Cancer Center and we are actively conducting several preclinical and clinical studies for our client partners.

Additionally, we develop our own proprietary compounds by in-licensing clinical stage compounds from pharma companies. The first compound is a dual-targeted anti-cancer molecule for hematologic and solid tumor malignancies under an agreement with Eisai Pharmaceuticals. Our first drug product is E6201, a small molecule dual mitogen-activated protein kinase/ FMS-like tyrosine kinase 3 (MEK1/FLT3) inhibitor. Our first indication for development is E6201 for the treatment of patients with relapsed or refractory acute myelogenous leukemia (AML). A second targeted compound is poised for in-licensure. Both compounds serve unmet needs for patients with gene mutations and failure of standard therapies for treatment of solid tumors and hematologic malignancies. We are poised to raise money as needed to assist in these development efforts.

ST currently has a Boston- and Texas-based Management Team with breadth and depth of skills, experience and track record for successful development of products from preclinical, manufacturing, clinical development, FDA submissions, maintenance, product approvals and life-cycle management.
Contact:
Strategia Therapeutics, Inc.
+1-781-761-0123 (office)
Contact@StrategiaTx.com (email)
StrategiaTx.com (website)

Strategia Therapeutics licensed in E6201 from Eisai, Japan: Dr. Keizo Koya, CEO and President of Strategia Therapeutics, truly wants to rescue promising shelved drug candidates to transform into valuable drugs for patients in need

Strategia Therapeutics licensed in E6201 from Eisai, Japan: Dr. Keizo Koya, CEO and President of Strategia Therapeutics, truly wants to rescue promising shelved drug candidates to transform into valuable drugs for patients in need

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